tert-butyl ((4-phenyltetrahydro-2H-pyran-4-yl)methyl)carbamate - Names and Identifiers
tert-butyl ((4-phenyltetrahydro-2H-pyran-4-yl)methyl)carbamate - Introduction
tert-butyl is an organic compound with the chemical formula C18H25NO3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: tert-butyl carbamate is a white solid.
-Solubility: It has good solubility in common organic solvents.
Use:
tert-butyl (methyl) caramate is commonly used in organic synthesis reactions as a protective group. It can protect the amino and phosphonium groups to prevent them from undesired reactions under certain reaction conditions. In addition, it can also be used to prepare precursors for active drugs or bioactive molecules.
Method:
The preparation method of tert-butyl (methyl)carbamate is mainly realized by chemical synthesis. The specific synthetic route may be slightly adjusted as needed, but the general steps are as follows: First synthesize 4-phenyltetrahydro-2H-pyran-4-one, it is then reacted with tert-butyl methyl isocyanate to give ((4-phenyltetrahydro-2H-pyran-4-yl) methyl) amine, which is then reacted with chloroformate to give the target compound.
Safety Information:
tert-butyl (methyl) caramate has low toxicity under normal use conditions and generally has no obvious harm. However, as an organic compound, it still needs to pay attention to safety measures during operation, such as wearing appropriate personal protective equipment (such as gloves and goggles) and avoiding direct contact with skin and eyes. At the same time, it should be properly stored and kept away from fire and oxidizing agents.
Last Update：2024-04-09 21:11:58